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Andrew V Gomez Selected Research

amlexanox (Aphthasol)

1/2021FGF21 is required for the metabolic benefits of IKKε/TBK1 inhibition.
11/2018Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKKε for the treatment of obesity.
10/2018Carboxylic Acid Derivatives of Amlexanox Display Enhanced Potency toward TBK1 and IKKε and Reveal Mechanisms for Selective Inhibition.
7/2017Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes.

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Andrew V Gomez Research Topics

Disease

4Obesity
01/2021 - 07/2017
3Insulin Resistance
01/2021 - 07/2017
2Weight Loss (Weight Reduction)
01/2021 - 11/2018
2Type 2 Diabetes Mellitus (MODY)
10/2018 - 07/2017
1Non-alcoholic Fatty Liver Disease
07/2017
1Fatty Liver
07/2017
1Inflammation (Inflammations)
07/2017
1Metabolic Diseases (Metabolic Disease)
07/2017

Drug/Important Bio-Agent (IBA)

4amlexanox (Aphthasol)FDA Link
01/2021 - 07/2017
3Phosphotransferases (Kinase)IBA
11/2018 - 07/2017
2Pharmaceutical PreparationsIBA
10/2018 - 07/2017
1Protein Kinases (Protein Kinase)IBA
01/2021
1fibroblast growth factor 21IBA
01/2021
1Interleukin-6 (Interleukin 6)IBA
11/2018
1NF-kappaB-Inducing KinaseIBA
11/2018
1Insulin (Novolin)FDA Link
11/2018
1Carboxylic AcidsIBA
11/2018
1Biological ProductsIBA
11/2018
1benzocycloheptapyridineIBA
11/2018
1Glucose (Dextrose)FDA LinkGeneric
07/2017

Therapy/Procedure

1Therapeutics
07/2017